437 Selective reduction of cytosolic ME1 expression and enzyme activity significantly reduces GSIS and amino acid-stimulated insulin secretion (AASIS)
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Storage and handling Keep refrigerated at 28C
Future mechanistic studies should use CVB-infected human islets to quantify the production, processing, and display of key autoantigens, utilizing proteomics or other methods, following infection-induced ER stress and comparing results to an inactivated virus as a control
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